My guinea pig has been sneezing for a few days and her breathing sounds crackly
By NetForPet Editorial ยท July 9, 2026
Get her to an exotics or small-mammal vet within the day. Guinea pigs with respiratory infections go downhill very fast, and this is the species where "let's give it a week" ends badly. And the hard line first: if she is breathing with her mouth open, if her nose or gums look bluish, or if she has stopped eating altogether, that is an emergency โ go now, tonight.
The reason for the urgency is a chain. A guinea pig who feels ill eats less. A guinea pig who eats less shuts her gut down within a day or two. Then you are treating two problems instead of one, and the second one is the one that kills her.
A critical safety point: never give her leftover antibiotics, or anything prescribed for another animal. Several very common antibiotics wipe out a guinea pig's gut bacteria and are fatal to this species. Only a vet who knows guinea pigs should choose the treatment.
Things to check and to raise at the appointment: the bedding โ dusty, scented, or pine and cedar shavings irritate airways, and ammonia from a cage that is overdue for a clean does real damage, so put your nose down at her level for a minute and be honest about what you smell. The new bedding brand is worth mentioning. Also the hay quality (dusty hay is a common culprit), the humidity, whether her cage-mate is sneezing too, and any new animal in the last few weeks.
The most useful thing you can do today, and it is genuinely powerful: weigh her every day on a kitchen scale, in grams, and write it down. A guinea pig's weight starts falling before anything else is visible; that daily number is the best early-warning system a guinea pig owner has. Keep her warm, keep hay in front of her, and don't delay the appointment to watch and see.
Keep reading
Bring your pet's whole world together
Join NetForPet โ free